{"entities":{"Q38613":{"pageid":28979,"ns":120,"title":"Item:Q38613","lastrevid":114190,"modified":"2026-08-13T03:45:33Z","type":"item","id":"Q38613","labels":{"mul":{"language":"mul","value":"2B6B"},"pt-br":{"language":"pt-br","value":"Neoplasias malignas da nasofaringe"},"en":{"language":"en","value":"Malignant neoplasms of nasopharynx"}},"descriptions":{"pt-br":{"language":"pt-br","value":"Uma grande variedade de tumores pode surgir na nasofaringe, mas \u00e9 o carcinoma da nasofaringe que fascinou gera\u00e7\u00f5es de oncologistas, patologistas, cientistas e epidemiologistas. Ele mostra diferen\u00e7as geogr\u00e1ficas marcantes, com alta taxa de incid\u00eancia no sul da China. Em algumas \u00e1reas end\u00eamicas, a incid\u00eancia diminuiu cerca de 30% ao longo dos anos 2000-2020, sugerindo que fatores ambientais ou de estilo de vida podem desempenhar um papel importante e que a doen\u00e7a \u00e9, at\u00e9 certo ponto, pode ser prevenida. O carcinoma nasofar\u00edngeo mostra uma associa\u00e7\u00e3o muito forte com a infec\u00e7\u00e3o pelo v\u00edrus Epstein-Barr (EBV), independentemente da origem \u00e9tnica dos pacientes. Essa associa\u00e7\u00e3o foi pioneira em um novo paradigma de utiliza\u00e7\u00e3o de testes sorol\u00f3gicos virais para o diagn\u00f3stico de c\u00e2ncer e para triagem em popula\u00e7\u00f5es de alto risco. O carcinoma nasofar\u00edngeo geralmente responde \u00e0 radioterapia, e o resultado cl\u00ednico melhorou muito ao longo dos anos, devido aos refinamentos no estadiamento e aos protocolos de terapia aprimorados. As caracter\u00edsticas histol\u00f3gicas incomuns e muitas vezes enganosas do carcinoma da nasofaringe geraram controv\u00e9rsias sobre a natureza do tumor e ainda representam um desafio para os patologistas cir\u00fargicos. Possivelmente, existiram mais nomes designados para os v\u00e1rios subtipos histol\u00f3gicos de carcinoma da nasofaringe do que qualquer outro tipo de tumor."},"en":{"language":"en","value":"A wide variety of tumours can arise in the nasopharynx, but it is nasopharyngeal carcinoma that has fascinated generations of oncologists, pathologists, scientists and epidemiologists. It shows marked geographic differences, with highest incidence rates in Southern China. In some endemic areas, the incidence has declined by about 30% over the years 2000-2020, suggesting that environmental or lifestyle factors may play a major role and that the disease is, to some extent, preventable.  Nasopharyngeal carcinoma shows a very strong association with Epstein-Barr virus (EBV) infection, irrespective of the ethnic origin of the patients. This association has pioneered a new paradigm of utilizing viral serological tests for the diagnosis of cancer and for screening in high-risk populations. Nasopharyngeal carcinoma is generally responsive to radiation therapy, and the clinical outcome has greatly improved over the years, due to refinements in staging and to improved therapy protocols. The unusual and often deceptive histological features of nasopharyngeal carcinoma have generated controversies over the nature of the tumour and still pose a challenge to surgical pathologists. There have possibly been more names invented for the various histological subtypes of nasopharyngeal carcinoma than any other tumour type."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"6c01670a380f5e1951d8ff37e5d796904b819d54","datavalue":{"value":"https://id.who.int/icd/entity/547578362","type":"string"},"datatype":"url"},"type":"statement","id":"Q38613$AD7F98A0-F80A-49B4-9850-AC2D9BEF8A71","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"ede0fb38cbdff0487ab6ca3a1d6e68d8bf02f63e","datavalue":{"value":"CID11:2B6B","type":"string"},"datatype":"string"},"type":"statement","id":"Q38613$93D528A0-A57D-4B13-BB4E-9021E58FC59B","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"da04f72aadcb743f43e5d74b25143aae06d89d54","datavalue":{"value":"dki-india-2B6B","type":"string"},"datatype":"string"},"type":"statement","id":"Q38613$05C0E4F7-3EB4-43E4-BBBD-0E322AD92E08","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q38613$78A0EC93-4490-4332-90E8-C1FE39470FCE","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q38613$F753399A-681C-40C6-83E8-3DF651FF1A0D","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"92b8222fcbb75718504f915073a3f43bd4003d18","datavalue":{"value":{"time":"+2026-08-13T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q38613$22535BBF-625A-46CE-BB2D-635473E24CD4","rank":"normal"}],"P89":[{"mainsnak":{"snaktype":"value","property":"P89","hash":"479fe4550194bc8dbd7e3744e95bffc78c8d215c","datavalue":{"value":{"entity-type":"item","numeric-id":13005,"id":"Q13005"},"type":"wikibase-entityid"},"datatype":"wikibase-item"},"type":"statement","id":"Q38613$851D0061-0B1E-49B2-848E-B3EA725879BE","rank":"normal"}]},"sitelinks":{}}}}