{"entities":{"Q106362":{"pageid":96759,"ns":120,"title":"Item:Q106362","lastrevid":615767,"modified":"2026-08-17T13:19:28Z","type":"item","id":"Q106362","labels":{"mul":{"language":"mul","value":"ID_1862698598"},"pt-br":{"language":"pt-br","value":"Mononeuropatia m\u00faltipla por vasculite na granulomatose de Wegener"},"en":{"language":"en","value":"Multiple mononeuropathy vasculitis with Wegener granulomatosis"}},"descriptions":{"pt-br":{"language":"pt-br","value":"A granulomatose de Wegner pode estar associada tanto \u00e0 mononeurite m\u00faltipla quanto a neuropatias sim\u00e9tricas. As neuropatias podem se desenvolver durante o curso da doen\u00e7a. Al\u00e9m das caracter\u00edsticas de neuropatia m\u00faltipla e neuropatias sim\u00e9tricas, o envolvimento de nervos cranianos (II, nervos extraoculares, V, VII, VIII, IX) ocorre e est\u00e1 relacionado ao processo granulomatoso caracter\u00edstico. Al\u00e9m disso, envolvimento do sistema renal, vias respirat\u00f3rias e pulm\u00e3o, e inflama\u00e7\u00e3o focal das cavidades oral e nasal. Ocorre infiltra\u00e7\u00e3o de vasos pequenos e m\u00e9dios na histologia e os granulomas s\u00e3o os achados mais frequentes._x000D_ Os anticorpos neurais associados s\u00e3o: pANCA (Anticorpos Perinucleares Anti-Neutr\u00f3filos Citoplasm\u00e1ticos) e c-ANCA (Anticorpos Anti-Neutr\u00f3filos Citoplasm\u00e1ticos da Proteinase 3)."},"en":{"language":"en","value":"Wegner`s granulomatosis can be associated with both mononeuritis multiplex as well as symmetric neuropathies. Neuropathies may develop during the course of the disease. In addition to the features of multiplex neuropathy and symmetric neuropathies, cranial nerve involvement (II, extraocular nerves, V, VII, VIII, IX) occurs and are related to the characteristic granulomatous process. In addition system involvement of kidneys, airways and lung, and focal inflammation of the oral and nasal cavities. Histologically small and midsize vessel infiltration occurs, granulomas are more frequent in CN. Associated neural antibodies are: pANCA (Perinuclear Anti-Neutrophil Cytoplasmic Antibodies) and c-ANCA (Proteinase 3 Anti-Neutrophil Cytoplasmic Antibodies)."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"f6a226a5f48d2c624d835c9fdf6b35dd5a86b282","datavalue":{"value":"https://id.who.int/icd/entity/1862698598","type":"string"},"datatype":"url"},"type":"statement","id":"Q106362$8557AE8B-AB0D-4334-929F-8D3C4B4EA360","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"f579abbb5a95b6e41906e6a18507ab88cac021c2","datavalue":{"value":"CID11:ID_1862698598","type":"string"},"datatype":"string"},"type":"statement","id":"Q106362$C02B90D4-2380-42F8-B4E7-3D4C492D3B2F","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"8f3e3d518b4cd1ed4779bfee134682bb36ce7ad9","datavalue":{"value":"dki-india-ID_1862698598","type":"string"},"datatype":"string"},"type":"statement","id":"Q106362$5C17EC21-AF57-4C46-BA1B-53855B31E6B4","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q106362$3B0D9641-C137-4EC2-A2DD-010AE7414E8F","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q106362$7408C073-9F0A-45C5-B629-5ED19BCC5A07","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"8612011b2ca718e4ec0db5a49d2de6d25b2e811c","datavalue":{"value":{"time":"+2026-08-16T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q106362$A21339DC-A43B-48CC-AD86-B270AAC0C3DA","rank":"normal"}]},"sitelinks":{}}}}