{"entities":{"Q104470":{"pageid":94868,"ns":120,"title":"Item:Q104470","lastrevid":602240,"modified":"2026-08-17T10:19:40Z","type":"item","id":"Q104470","labels":{"mul":{"language":"mul","value":"ID_93488909"},"pt-br":{"language":"pt-br","value":"Defici\u00eancia de carnitina palmitoiltransferase II, forma miop\u00e1tica"},"en":{"language":"en","value":"Carnitine palmitoyltransferase II deficiency, myopathic form"}},"descriptions":{"pt-br":{"language":"pt-br","value":"A forma miop\u00e1tica da defici\u00eancia de carnitina palmitoiltransferase II \u00e9 um transtorno metab\u00f3lico heredit\u00e1rio que afeta a oxida\u00e7\u00e3o mitocondrial de \u00e1cidos graxos de cadeia longa. \u00c9 a forma mais comum e menos grave de defici\u00eancia de CPT II. As manifesta\u00e7\u00f5es cl\u00ednicas s\u00e3o caracterizadas por epis\u00f3dios recorrentes de rabdomi\u00f3lise, dor muscular e fraqueza desencadeada geralmente por exerc\u00edcios f\u00edsicos prolongados e \u00e0s vezes exacerbada por extremos de temperatura. Estes epis\u00f3dios tamb\u00e9m podem ser provocados ou exacerbados por jejum prolongado, assim como podem ocorrer durante doen\u00e7as virais."},"en":{"language":"en","value":"The myopathic form of carnitine palmitoyltransferase II (CPT II) deficiency, an inherited metabolic disorder that affects mitochondrial oxidation of long chain fatty acids (LCFA), is the most common and the least severe form of CPT II deficiency. The clinical manifestations are characterised by recurrent attacks of rhabdomyolysis, muscle pain, and weakness triggered usually by prolonged physical exercise and sometimes exacerbated by extremes in temperature; episodes may also be provoked or exacerbated by prolonged fasting, such as may occur with intercurrent viral illness."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"885c086c7d17bae1f509fda0c0933ebb012d859c","datavalue":{"value":"https://id.who.int/icd/entity/93488909","type":"string"},"datatype":"url"},"type":"statement","id":"Q104470$81E762BC-0383-44DD-8FFE-B703839E9E73","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"d92324349f098fbda24bdc2823a8440dedbd7135","datavalue":{"value":"CID11:ID_93488909","type":"string"},"datatype":"string"},"type":"statement","id":"Q104470$8258E4A3-9A31-40F6-9F95-13C24294C2A4","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"796413240d4343a32d76a7814b4c1398a30328be","datavalue":{"value":"dki-india-ID_93488909","type":"string"},"datatype":"string"},"type":"statement","id":"Q104470$F9FDEF8C-B823-4E78-BE18-E4F8F7A2BB4A","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q104470$6B439E41-FB69-40EC-94BB-D8E200587D4C","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q104470$A9EAF028-00E6-4E61-BB22-FF91161564C3","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"8612011b2ca718e4ec0db5a49d2de6d25b2e811c","datavalue":{"value":{"time":"+2026-08-16T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q104470$A1AA0CE5-678F-4EEC-BF7D-677C0090830D","rank":"normal"}]},"sitelinks":{}}}}