{"entities":{"Q104377":{"pageid":94775,"ns":120,"title":"Item:Q104377","lastrevid":601577,"modified":"2026-08-17T10:14:07Z","type":"item","id":"Q104377","labels":{"mul":{"language":"mul","value":"ID_1137579941"},"pt-br":{"language":"pt-br","value":"Enteropatia autoimune tipo 3"},"en":{"language":"en","value":"Autoimmune enteropathy type 3"}},"descriptions":{"pt-br":{"language":"pt-br","value":"Enteropatia autoimune (AIE) \u00e9 uma condi\u00e7\u00e3o rara caracterizada por diarreia intrat\u00e1vel, altera\u00e7\u00f5es histol\u00f3gicas na bi\u00f3psia do intestino delgado, falha na resposta \u00e0 manipula\u00e7\u00e3o diet\u00e9tica que tamb\u00e9m pode apresentar manifesta\u00e7\u00f5es extraintestinais. Em muitos pacientes, terapias imunossupressoras s\u00e3o necess\u00e1rias. Embora a AIE seja mais comum em beb\u00eas, o envolvimento em adultos tamb\u00e9m foi documentado. IPEX (s\u00edndrome de desregula\u00e7ao imune, poliendocrinopatia e enteropatia ligada ao X) ou APECED (Fen\u00f4menos Autoimunes, Poliendocrinopatia, Candid\u00edase e Distrofia Ectod\u00e9rmica) s\u00e3o formas sist\u00eamicas de AIE."},"en":{"language":"en","value":"Autoimmune Enteropathy (AIE) is a rare condition characterised by intractable diarrhoea, histologic changes on small intestinal biopsy, failed response to dietary manipulation that also may present with extra-intestinal manifestations. In many patients, immunosuppressive therapies are necessary. Although AIE is more common in infants, adult involvement has also been documented. IPEX (Immunodysregulation Polyendocrinopathy Enteropathy X-linked Syndrome) or APECED (Autoimmune Phenomena, Polyendocrinopathy, Candidiasis, and Ectodermal Dystrophy) are systemic forms of AIE."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"412a87afe02b992d622e9f58db1654dcccef5617","datavalue":{"value":"https://id.who.int/icd/entity/1137579941","type":"string"},"datatype":"url"},"type":"statement","id":"Q104377$0870F5F1-A9B0-4D1A-A7B8-8A9605FB6F0E","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"8c1f5ae76e7b1ef89646efc3686943623d9758d8","datavalue":{"value":"CID11:ID_1137579941","type":"string"},"datatype":"string"},"type":"statement","id":"Q104377$94A6C22D-6ED6-4362-B382-1A79817CE856","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"656cca1a9dd6b3f874536bf820c6fcd276472527","datavalue":{"value":"dki-india-ID_1137579941","type":"string"},"datatype":"string"},"type":"statement","id":"Q104377$91769B6F-184A-48C4-B749-0D7A193123B9","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q104377$518F872B-E5CE-43DE-8150-9402B5590165","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q104377$D83C625F-1850-4F31-BE83-613ED54819A6","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"8612011b2ca718e4ec0db5a49d2de6d25b2e811c","datavalue":{"value":{"time":"+2026-08-16T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q104377$B1173514-B52B-4983-B7DA-8DEFB8FC05ED","rank":"normal"}]},"sitelinks":{}}}}