{"entities":{"Q104269":{"pageid":94667,"ns":120,"title":"Item:Q104269","lastrevid":600782,"modified":"2026-08-17T10:08:01Z","type":"item","id":"Q104269","labels":{"mul":{"language":"mul","value":"ID_1476045360"},"pt-br":{"language":"pt-br","value":"Doen\u00e7a de Charcot-Marie-Tooth tipo 2E"},"en":{"language":"en","value":"Charcot-Marie-Tooth disease type 2E"}},"descriptions":{"pt-br":{"language":"pt-br","value":"A doen\u00e7a de Charcot-Marie-Tooth autoss\u00f4mica dominante tipo 2E (CMT2E) \u00e9 uma forma de doen\u00e7a de Charcot-Marie-Tooth axonal, uma neuropatia perif\u00e9rica sensitivomotora. O in\u00edcio do CMT2E ocorre na primeira \u00e0 sexta d\u00e9cada com um transtorno de marcha e uma fraqueza nas pernas que acomete os bra\u00e7os secundariamente. Os reflexos tendinosos est\u00e3o reduzidos ou ausentes e, ap\u00f3s anos, todos os pacientes apresentam p\u00e9s cavos. Outros sinais podem estar presentes, incluindo perda auditiva e tremor postural."},"en":{"language":"en","value":"Autosomal dominant Charcot-Marie-Tooth disease type 2E (CMT2E) is a form of axonal Charcot-Marie-Tooth disease, a peripheral sensorimotor neuropathy. CMT2E onset is in the first to 6th decade with a gait anomaly and a leg weakness that reaches the arms secondarily. Tendon reflexes are reduced or absent and, after years, all patients have a pes cavus. Other signs may be present, including hearing loss and postural tremor."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"591730785205e054dc731e7b5c5edc277270af4c","datavalue":{"value":"https://id.who.int/icd/entity/1476045360","type":"string"},"datatype":"url"},"type":"statement","id":"Q104269$10B6E357-183A-43E5-ABD6-A579F5FB4D3E","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"f2029f70f5164adf93a9fcf29b0020f15f00a4bd","datavalue":{"value":"CID11:ID_1476045360","type":"string"},"datatype":"string"},"type":"statement","id":"Q104269$1E197B47-1BAB-4D53-A9A7-4686BBF65665","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"76e10bf86c57c4ab2c676cceb83e53d22b3788ed","datavalue":{"value":"dki-india-ID_1476045360","type":"string"},"datatype":"string"},"type":"statement","id":"Q104269$3A1498A9-5650-45B2-9335-F9C4A56CE44A","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q104269$F2F4DEE2-F249-4C30-9163-77E0208440EA","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q104269$4E892DD8-C0EE-4B72-BA18-27BF20182AFA","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"8612011b2ca718e4ec0db5a49d2de6d25b2e811c","datavalue":{"value":{"time":"+2026-08-16T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q104269$0158E7A2-6225-44A8-BE48-EDBCCFF90EC1","rank":"normal"}]},"sitelinks":{}}}}