{"entities":{"Q100996":{"pageid":91389,"ns":120,"title":"Item:Q100996","lastrevid":577058,"modified":"2026-08-16T17:47:04Z","type":"item","id":"Q100996","labels":{"mul":{"language":"mul","value":"ID_1471347177"},"pt-br":{"language":"pt-br","value":"Neuropatia sensitivo-motora paraneopl\u00e1sica, autoanticorpo neuronal positivo"},"en":{"language":"en","value":"Paraneoplastic sensorimotor neuropathy, neural autoantibody positive"}},"descriptions":{"pt-br":{"language":"pt-br","value":"A neuropatia sensitivo motora paraneopl\u00e1sica ocorre como um efeito remoto em pacientes com c\u00e2ncer e linfoma em uma frequ\u00eancia indeterminada. \u00c9 uma neuropatia sensitivo motora at\u00edpica com componentes motores e sensoriais mistos, tamb\u00e9m com uma grande varia\u00e7\u00e3o de express\u00e3o cl\u00ednica. A neuropatia pode ocorrer na primeira apresenta\u00e7\u00e3o do c\u00e2ncer, ou aparecer no curso tardio, onde deve ser diferenciada da toxicidade do tratamento, sequelas de perda de peso e hipovitaminose._x000D_ A associa\u00e7\u00e3o com anticorpos onconeurais como biomarcadores \u00e9 pobre e mais comumente relacionada a anticorpos anti-Hu e anti-CV2 / CRMP-5 (prote\u00edna 5 do mediador da resposta \u00e0 colapsina)."},"en":{"language":"en","value":"Paraneoplastic sensorimotor neuropathy occurs as a remote effect in cancer and lymphoma patients in an undetermined frequency. It is an uncharacteristic sensorimotor neuropathy with mixed motor and sensory component also with a large variance of clinical expression. The neuropathy can occur at the first presentation of the cancer, or appear in the later course, where it has to be distinguished from treatment toxicity, sequelae of weight loss and hypovitaminosis.  The association with onconeural antibodies as biomarkers is poor and most commonly related to autoantibodies anti-Hu and anti-CV2/CRMP-5 (collapsin response mediator protein 5) antibodies."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"4aa723a6bec24dada5bdd2e10e07c29c8d4c983e","datavalue":{"value":"https://id.who.int/icd/entity/1471347177","type":"string"},"datatype":"url"},"type":"statement","id":"Q100996$4A45ABF8-A158-4F08-91B1-4BFC80F8B770","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"b5f519aeefef57bd22b25159b505a9a67feb3bc6","datavalue":{"value":"CID11:ID_1471347177","type":"string"},"datatype":"string"},"type":"statement","id":"Q100996$081AC744-CE6C-473B-8EA4-1510C4CEC41E","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"f40972c87dca96f86393494dde46e81a65604137","datavalue":{"value":"dki-india-ID_1471347177","type":"string"},"datatype":"string"},"type":"statement","id":"Q100996$1EB41AB6-3522-42EE-A991-330DE90FC9E7","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q100996$2DEBA2FE-F563-4930-B31E-A486EBD00CE8","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q100996$AF957C8D-9D4D-4DC0-B5FE-063DEAD35C08","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"378ac503ed43f21e1f461d2823a6ad59da580514","datavalue":{"value":{"time":"+2026-08-15T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q100996$D5ECACE3-5DC4-4D95-AE61-51E67A50CA37","rank":"normal"}]},"sitelinks":{}}}}