{"entities":{"Q100772":{"pageid":91165,"ns":120,"title":"Item:Q100772","lastrevid":575427,"modified":"2026-08-16T17:31:59Z","type":"item","id":"Q100772","labels":{"mul":{"language":"mul","value":"ID_1488729253"},"pt-br":{"language":"pt-br","value":"Miopatia de agregados tubulares"},"en":{"language":"en","value":"Myopathy with tubular aggregates"}},"descriptions":{"pt-br":{"language":"pt-br","value":"A miopatia de agregados tubulares \u00e9 uma entidade nosol\u00f3gica rara, geneticamente heterog\u00eanea, caracterizada por agregados tubulares como a principal marca patol\u00f3gica na bi\u00f3psia muscular. Os agregados tubulares s\u00e3o arranjos regulares de t\u00fabulos derivados do ret\u00edculo sarcoplasm\u00e1tico e tamb\u00e9m podem ocasionalmente ser encontrados como uma caracter\u00edstica associada em outras miopatias heredit\u00e1rias ou s\u00edndromes miast\u00eanicas cong\u00eanitas. A forma pura \u00e9 geralmente espor\u00e1dica ou segue um modo de heran\u00e7a autoss\u00f4mico dominante e \u00e9 clinicamente caracterizada por mialgias, c\u00e3ibras e rigidez muscular, com ou sem fraqueza com uma distribui\u00e7\u00e3o predominantemente proximal."},"en":{"language":"en","value":"Tubular aggregate myopathy is a genetically heterogeneous, rare nosological entity characterised by tubular aggregates as the main pathological hallmark on muscle biopsy. Tubular aggregates are regular arrays of tubules derived from the sarcoplasmic reticulum and can also occasionally be found as an accompanying feature in other hereditary myopathies or congenital myasthenic syndromes. Pure form is usually sporadic or follows an autosomal dominant mode of inheritance, and is clinically characterised by myalgias, cramps and muscle stiffness, with or without weakness with a predominantly proximal distribution."}},"aliases":{},"claims":{"P68":[{"mainsnak":{"snaktype":"value","property":"P68","hash":"61e75cfdd4165be18bef272cbbbccccfba503239","datavalue":{"value":"https://id.who.int/icd/entity/1488729253","type":"string"},"datatype":"url"},"type":"statement","id":"Q100772$44847370-8137-4A79-B98F-82F3CF9C0325","rank":"normal"}],"P67":[{"mainsnak":{"snaktype":"value","property":"P67","hash":"632b79afccd02f10faaedac098cb57dd4006ccbf","datavalue":{"value":"CID11:ID_1488729253","type":"string"},"datatype":"string"},"type":"statement","id":"Q100772$FE960C67-D157-4BA4-970F-124DE7BF8708","rank":"normal"}],"P70":[{"mainsnak":{"snaktype":"value","property":"P70","hash":"2ca714ba7d86b4a10e4a0ae9ebae3324c8a7bdb5","datavalue":{"value":"dki-india-ID_1488729253","type":"string"},"datatype":"string"},"type":"statement","id":"Q100772$D7B2DD99-5C23-4478-A3D8-FDFE179FCE2D","rank":"normal"}],"P86":[{"mainsnak":{"snaktype":"value","property":"P86","hash":"a96031634b9f5dafddaf781bbba3adea6bb64ef4","datavalue":{"value":"Conclu\u00eddo","type":"string"},"datatype":"string"},"type":"statement","id":"Q100772$1BDE1B81-D807-4FB8-BD63-A72FC5D1A0B0","rank":"normal"}],"P78":[{"mainsnak":{"snaktype":"value","property":"P78","hash":"5f9b5be68b7400da549761cf15abfdbc4d1e075b","datavalue":{"value":"https://pauloleads.com.br/cases-publicos/","type":"string"},"datatype":"url"},"type":"statement","id":"Q100772$2F7FFA77-EC04-44AA-9262-1DAD76DD54A7","rank":"normal"}],"P80":[{"mainsnak":{"snaktype":"value","property":"P80","hash":"378ac503ed43f21e1f461d2823a6ad59da580514","datavalue":{"value":{"time":"+2026-08-15T00:00:00Z","timezone":0,"before":0,"after":0,"precision":11,"calendarmodel":"http://www.wikidata.org/entity/Q1985727"},"type":"time"},"datatype":"time"},"type":"statement","id":"Q100772$82478817-33A6-482F-972C-04FB5046FD23","rank":"normal"}]},"sitelinks":{}}}}