Infantile cortical hyperostosis (Q98922)

Infantile cortical hyperostosis or Caffey disease is a rare condition which presents most commonly in infants who present with irritability, pain, tenderness, hyperaesthesia, soft tissue swelling and redness involving one or several areas of the body. Systemic changes with fever are usually present in the early stages. The pain may be severe enough to result in pseudoparalysis and individual nerve involvement may result in true localised palsies. Other reported clinical findings include dysphagia and nasal obstruction.