Cloverleaf skull - multiple congenital anomalies (Q94156)

Cloverleaf skull - multiple congenital anomalies syndrome is characterised by cloverleaf skull, limb anomalies, facial dysmorphism and multiple congenital anomalies. Dysmorphic features include protruding forehead, hypertelorism, broad nasal bridge, wide anterior fontanel, short philtrum, downturning mouth, micrognathia and low-set ears. The limbs show rhizomelic shortening.