Dowling-Degos disease (Q93301)

Dowling-Degos disease is a rare autosomal dominant condition which usually presents post-pubertally with multiple small, round pigmented freckle-like macules. They become progressively more numerous and may become reticulate with time. The axillae and groins are the usual sites, although other areas may be involved, including the intergluteal and inframammary folds, neck, scalp, trunk, arms and genitalia. Pigmentation is symmetrical and progressive, but is otherwise asymptomatic.