Eccrine syringosquamous metaplasia (Q90209)
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Eccrine syringosquamous metaplasia describes a distinctive microscopic finding of eccrine duct damage in which an insult, most commonly cytotoxic chemotherapy, has resulted in a transformation from the normal cuboidal to squamous epithelium, which may simulate squamous cell carcinoma. Patients present with erythematous papules, often in a generalised distribution and sometimes with vesicles and pustules. It may also present with acral erythema. Drugs implicated include cytarabine, doxorubicin, cis-platinum and protein kinase inhibitors.
| Language | Label | Description | Also known as |
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| default for all languages | ID_407987403 |
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| English | Eccrine syringosquamous metaplasia |
Eccrine syringosquamous metaplasia describes a distinctive microscopic finding of eccrine duct damage in which an insult, most commonly cytotoxic chemotherapy, has resulted in a transformation from the normal cuboidal to squamous epithelium, which may simulate squamous cell carcinoma. Patients present with erythematous papules, often in a generalised distribution and sometimes with vesicles and pustules. It may also present with acral erythema. Drugs implicated include cytarabine, doxorubicin, cis-platinum and protein kinase inhibitors. |
