Immunodeficiency due to selective anti-polysaccharide antibody deficiency (Q88856)

Immunodeficiency due to selective anti-polysaccharide antibody deficiency is characterised by normal immunoglobulin levels (including IgG sub-classes) but impaired polysaccharide responsiveness (IPR). This syndrome is a rare primary immunodeficiency characterised by recurrent bacterial infections, mostly of the respiratory tract. The offending bacteria are those with a polysaccharide capsule, such as pneumococci, Hemophilus influenzae, meningococci and group B streptococci.