Erdheim-Chester disease (Q67672)
From determinar.ia.br - Determine suas informações
Erdheim-Chester disease is a Class IIa (non-Langerhans cell) histiocytosis of unknown aetiology characterised by a xanthogranulomatous infiltration of viscera, bones, retroperitoneum and skin by lipid-laden histiocytes and surrounding fibrosis. It most commonly presents in adult life with bone pain, typically around the knees and ankles. Exophthalmos, diabetes insipidus, cutaneous xanthomata, pulmonary fibrosis and a broad range of complications resulting from retroperitoneal and CNS infiltration are all well recognised.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | ID_1395439137 |
||
| English | Erdheim-Chester disease |
Erdheim-Chester disease is a Class IIa (non-Langerhans cell) histiocytosis of unknown aetiology characterised by a xanthogranulomatous infiltration of viscera, bones, retroperitoneum and skin by lipid-laden histiocytes and surrounding fibrosis. It most commonly presents in adult life with bone pain, typically around the knees and ankles. Exophthalmos, diabetes insipidus, cutaneous xanthomata, pulmonary fibrosis and a broad range of complications resulting from retroperitoneal and CNS infiltration are all well recognised. |
