AL amyloidosis (Q40143)
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AL (Amyloid Light-Chain) Amyloidosis is due to the deposition of immunoglobulin light chains in glomeruli where they are seen as Congo red binding fibrils and immuno-stain specifically for kappa or lambda light chains. By light microscopy there is amorphous hyaline material in the mesangium and capillary walls. A light chain producing plasma cell or B-cell dysplasia is responsible. Other organs are also involved in this systemic disease.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | 5D00.0 |
||
| English | AL amyloidosis |
AL (Amyloid Light-Chain) Amyloidosis is due to the deposition of immunoglobulin light chains in glomeruli where they are seen as Congo red binding fibrils and immuno-stain specifically for kappa or lambda light chains. By light microscopy there is amorphous hyaline material in the mesangium and capillary walls. A light chain producing plasma cell or B-cell dysplasia is responsible. Other organs are also involved in this systemic disease. |
Statements
CID11:5D00.0
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