Motor neuron disease in autoimmune disease including increased anti-GMl ganglioside antibody (Q101489)
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There is a higher incidence of motor neuron disease (MND) in patients with preceding autoimmune disease, suggesting possible shared genetic or environmental risk factors. Occasional reports have documented the coexistence of MND with symptomatic autoimmune disease. Multifocal motor neuropathy (MMN), a mimic of MND, may be associated with anti GM1 ganglioside antibodies. Low-titre anti-GM1 ganglioside antibodies may be detected in patients with MND, without clinical or neurophysiological features of MMN.
| Language | Label | Description | Also known as |
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| default for all languages | ID_955868778 |
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| English | Motor neuron disease in autoimmune disease including increased anti-GMl ganglioside antibody |
There is a higher incidence of motor neuron disease (MND) in patients with preceding autoimmune disease, suggesting possible shared genetic or environmental risk factors. Occasional reports have documented the coexistence of MND with symptomatic autoimmune disease. Multifocal motor neuropathy (MMN), a mimic of MND, may be associated with anti GM1 ganglioside antibodies. Low-titre anti-GM1 ganglioside antibodies may be detected in patients with MND, without clinical or neurophysiological features of MMN. |
