Juvenile dermatomyositis with calcinosis (Q92514)

Juvenile dermatomyositis with calcinosis is a rare childhood systemic autoimmune disease characterised by proximal muscle weakness, rashes due to chronic muscle and skin inflammation, and calcinosis due to the abnormal deposition of insoluble calcium salts within the skin, subcutaneous tissue, myofascia, or muscle. The sites most frequently affected by calcinosis are the elbows, knees, trunk, hands, feet, buttocks, and head, although it may occur virtually anywhere over the body. The onset of calcinosis is most often 1-3 years after illness onset but it can occur from the time of illness onset to as long as 20 years later.