Atopic keratoconjunctivitis (Q85776)

Atopic keratoconjunctivitis is a persistent allergic inflammatory, bilateral condition involving the eyelids, the conjunctiva, and possibly the cornea and can be defined as the ocular manifestation of atopic dermatitis. The hallmark sign is eczematous lesion of the eyelid, which tends to thicken, indurate, and fissure. The conjunctival redness and chemosis affect predominantly the inferior fornix and palpebral conjunctiva emerges in young adults and continues through the fifth decade of life, with a peak incidence between the age of 30–50. Complications can include conjunctival fibrosis, herpes simplex keratitis, keratoconus, retinal detachment, or cataracts, leading to sustained deterioration of vision.