Papular xanthoma (Q52482)

Papular xanthoma is a rare benign histiocytic disorder of unknown aetiology which may occur both in adults and children. It is characterised by yellow or reddish-yellow papules and nodules affecting both skin and mucous membranes. The back and head are most commonly affected. Histologically, there is an upper- and mid-dermal infiltrate of foamy histiocytes and giant cells. In adults the disease may be progressive whereas in children slow spontaneous resolution is the norm.