Basement membrane splitting and changes consistent with Alport syndrome (Q101055)

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Electron microscopy shows characteristic irregular thinning, basket weaving and lamellation of the glomerular basement membrane in established disease. Abnormalities in type 4 collagen are found in Alports disease. Hearing loss and other features of Alports syndrome may be present and the combination of clinical and pathology observations may lead to that diagnosis
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    Basement membrane splitting and changes consistent with Alport syndrome
    Electron microscopy shows characteristic irregular thinning, basket weaving and lamellation of the glomerular basement membrane in established disease. Abnormalities in type 4 collagen are found in Alports disease. Hearing loss and other features of Alports syndrome may be present and the combination of clinical and pathology observations may lead to that diagnosis

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