Pitted keratolysis (Q91582)

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Pitted keratolysis is a dermatosis of plantar skin caused by digestion of epidermal keratin by bacteria. Various bacteria including Kytococcus sedentarius, Dermatophilus congolensis and species of Corynebacterium, Actinomyces and Streptomyces. Prolonged occlusion and hyperhidrosis predispose to bacterial proliferation and the production of bacterial proteinases which destroy the stratum corneum, creating multiple pits. The affected skin is often white and macerated as a result of the accompanying hyperhidrosis.
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    Pitted keratolysis
    Pitted keratolysis is a dermatosis of plantar skin caused by digestion of epidermal keratin by bacteria. Various bacteria including Kytococcus sedentarius, Dermatophilus congolensis and species of Corynebacterium, Actinomyces and Streptomyces. Prolonged occlusion and hyperhidrosis predispose to bacterial proliferation and the production of bacterial proteinases which destroy the stratum corneum, creating multiple pits. The affected skin is often white and macerated as a result of the accompanying hyperhidrosis.

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