Chronic neuropathic pain after peripheral nerve injury (Q89871)

Chronic neuropathic pain after peripheral nerve injury is persistent or recurrent neuropathic pain caused by a peripheral nerve lesion. History of a plausible nerve trauma, pain onset in temporal relation to the trauma, and pain distribution within the innervation territory of a peripheral nerve(s) are required for the diagnosis. The pain may be spontaneous or evoked, as an increased response to a painful stimulus (hyperalgesia) or a painful response to a normally nonpainful stimulus (allodynia). Negative (e.g., decreased or loss of sensation) and positive sensory symptoms or signs (e.g., allodynia or hyperalgesia) must be compatible with the innervation territory of the affected nerve(s). Formation of a neuroma may lead to pain at the lesion site.