Transient congenital hypothyroidism due to transplacental passage of maternal TSH receptor blocking antibodies (Q86204)

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Transient congenital hypothyroidism can result from transplacental passage of maternal TSH-binding inhibitory antibodies. This occurs in mothers with autoimmune thyroiditis where immunoglobulin G (IgG) antithyroid antibodies are transmitted across the placenta and block TSH binding sites on the fetal thyroid. This form of congenital hypothyroidism generally resolves within the first 2 to 3 months of life.
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    Transient congenital hypothyroidism due to transplacental passage of maternal TSH receptor blocking antibodies
    Transient congenital hypothyroidism can result from transplacental passage of maternal TSH-binding inhibitory antibodies. This occurs in mothers with autoimmune thyroiditis where immunoglobulin G (IgG) antithyroid antibodies are transmitted across the placenta and block TSH binding sites on the fetal thyroid. This form of congenital hypothyroidism generally resolves within the first 2 to 3 months of life.

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