Bartter syndrome with hypocalcaemia (Q85250)

This is a rare inherited defect in the thick ascending limb of the loop of Henle. It is characterised by low potassium levels (hypokalaemia), increased blood pH (alkalosis), and normal to low blood pressure in the presence of low serum calcium levels in the blood (hypocalcaemia), specifically less than 2.1 mmol/L or 9 mg/dl or an ionized calcium level of less than 1.1 mmol/L or 4.5 mg/dL.