Microvillous inclusion disease (Q107203): Difference between revisions
From determinar.ia.br - Determine suas informações
Created a new Item |
Changed label, description and/or aliases in pt-br, en |
||
| description / pt-br | description / pt-br | ||
A doença de inclusão das microvilosidades (DIM) ou atrofia das microvilosidades é um transtorno congênito das células epiteliais intestinais que se apresenta com diarreia aquosa persistente com risco de vida e é caracterizada por anormalidades morfológicas dos enterócitos. Este é um transtorno genético raro que é herdado em um padrão autossômico recessivo. É causada por uma falta congênita de microvilosidades apicais nas células epiteliais do intestino delgado, no entanto, geralmente não possui a infiltração linfocítica intraepitelial característica do espru celíaco e apresenta coloração positiva para antígeno carcinoembrionário (CEA)._x000D_ A DIM manifesta-se nos primeiros dias de vida (forma de início precoce) ou nos primeiros dois meses (forma de início tardio) de vida. | |||
| description / en | description / en | ||
Microvillous inclusion disease (MVID) or microvillous atrophy is a congenital disorder of the intestinal epithelial cells that presents with persistent life-threatening watery diarrhoea and is characterised by morphological enterocyte abnormalities. This is a rare genetic disorder that is inherited in an autosomal recessive pattern. It is caused by a congenital lack of apical microvilli in the epithelial cells of the small intestine, however, it usually lacks the intraepithelial lymphocytic infiltration characteristic of celiac sprue and stains positive for carcinoembryonic antigen (CEA). MVID manifests either in the first days of life (early-onset form) or in the first two months (late-onset form) of life. | |||
Revision as of 14:11, 17 August 2026
Microvillous inclusion disease (MVID) or microvillous atrophy is a congenital disorder of the intestinal epithelial cells that presents with persistent life-threatening watery diarrhoea and is characterised by morphological enterocyte abnormalities. This is a rare genetic disorder that is inherited in an autosomal recessive pattern. It is caused by a congenital lack of apical microvilli in the epithelial cells of the small intestine, however, it usually lacks the intraepithelial lymphocytic infiltration characteristic of celiac sprue and stains positive for carcinoembryonic antigen (CEA). MVID manifests either in the first days of life (early-onset form) or in the first two months (late-onset form) of life.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | ID_2137578537 |
||
| English | Microvillous inclusion disease |
Microvillous inclusion disease (MVID) or microvillous atrophy is a congenital disorder of the intestinal epithelial cells that presents with persistent life-threatening watery diarrhoea and is characterised by morphological enterocyte abnormalities. This is a rare genetic disorder that is inherited in an autosomal recessive pattern. It is caused by a congenital lack of apical microvilli in the epithelial cells of the small intestine, however, it usually lacks the intraepithelial lymphocytic infiltration characteristic of celiac sprue and stains positive for carcinoembryonic antigen (CEA). MVID manifests either in the first days of life (early-onset form) or in the first two months (late-onset form) of life. |
