Kimura disease (Q105819): Difference between revisions

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Doença de Kimura é um transtorno inflamatório crônico de etiologia pouco compreendida, que mais comumente se manifesta com linfadenopatia ou massas subcutâneas indolores nas regiões de cabeça e pescoço em adultos jovens; pode causar desfiguração significativa. Histologicamente, os linfonodos estão infiltrados por densos agregados de eosinófilos, algumas vezes formando abscessos eosinofílicos. Este transtorno está associado a eosinofilia periférica e IgE sérica elevada. Está associado a síndrome nefrótica em até 20% dos pacientes.
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Kimura disease is a chronic inflammatory disorder of poorly understood aetiology that most commonly presents as painless lymphadenopathy or subcutaneous masses in the head and neck region in young adults: it may cause significant disfigurement. Histologically lymph nodes are infiltrated by dense aggregates of eosinophils, sometimes forming eosinophilic abscesses. The disorder is associated with peripheral eosinophilia and elevated serum IgE. It is associated with nephrotic syndrome in up to 20% of patients.

Revision as of 12:18, 17 August 2026

Kimura disease is a chronic inflammatory disorder of poorly understood aetiology that most commonly presents as painless lymphadenopathy or subcutaneous masses in the head and neck region in young adults: it may cause significant disfigurement. Histologically lymph nodes are infiltrated by dense aggregates of eosinophils, sometimes forming eosinophilic abscesses. The disorder is associated with peripheral eosinophilia and elevated serum IgE. It is associated with nephrotic syndrome in up to 20% of patients.
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ID_1229046951
    English
    Kimura disease
    Kimura disease is a chronic inflammatory disorder of poorly understood aetiology that most commonly presents as painless lymphadenopathy or subcutaneous masses in the head and neck region in young adults: it may cause significant disfigurement. Histologically lymph nodes are infiltrated by dense aggregates of eosinophils, sometimes forming eosinophilic abscesses. The disorder is associated with peripheral eosinophilia and elevated serum IgE. It is associated with nephrotic syndrome in up to 20% of patients.

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