Paraneoplastic sensorimotor neuropathy, neural autoantibody positive (Q100996): Difference between revisions
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A neuropatia sensitivo motora paraneoplásica ocorre como um efeito remoto em pacientes com câncer e linfoma em uma frequência indeterminada. É uma neuropatia sensitivo motora atípica com componentes motores e sensoriais mistos, também com uma grande variação de expressão clínica. A neuropatia pode ocorrer na primeira apresentação do câncer, ou aparecer no curso tardio, onde deve ser diferenciada da toxicidade do tratamento, sequelas de perda de peso e hipovitaminose._x000D_ A associação com anticorpos onconeurais como biomarcadores é pobre e mais comumente relacionada a anticorpos anti-Hu e anti-CV2 / CRMP-5 (proteína 5 do mediador da resposta à colapsina). | |||
| description / en | description / en | ||
Paraneoplastic sensorimotor neuropathy occurs as a remote effect in cancer and lymphoma patients in an undetermined frequency. It is an uncharacteristic sensorimotor neuropathy with mixed motor and sensory component also with a large variance of clinical expression. The neuropathy can occur at the first presentation of the cancer, or appear in the later course, where it has to be distinguished from treatment toxicity, sequelae of weight loss and hypovitaminosis. The association with onconeural antibodies as biomarkers is poor and most commonly related to autoantibodies anti-Hu and anti-CV2/CRMP-5 (collapsin response mediator protein 5) antibodies. | |||
Revision as of 17:47, 16 August 2026
Paraneoplastic sensorimotor neuropathy occurs as a remote effect in cancer and lymphoma patients in an undetermined frequency. It is an uncharacteristic sensorimotor neuropathy with mixed motor and sensory component also with a large variance of clinical expression. The neuropathy can occur at the first presentation of the cancer, or appear in the later course, where it has to be distinguished from treatment toxicity, sequelae of weight loss and hypovitaminosis. The association with onconeural antibodies as biomarkers is poor and most commonly related to autoantibodies anti-Hu and anti-CV2/CRMP-5 (collapsin response mediator protein 5) antibodies.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | ID_1471347177 |
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| English | Paraneoplastic sensorimotor neuropathy, neural autoantibody positive |
Paraneoplastic sensorimotor neuropathy occurs as a remote effect in cancer and lymphoma patients in an undetermined frequency. It is an uncharacteristic sensorimotor neuropathy with mixed motor and sensory component also with a large variance of clinical expression. The neuropathy can occur at the first presentation of the cancer, or appear in the later course, where it has to be distinguished from treatment toxicity, sequelae of weight loss and hypovitaminosis. The association with onconeural antibodies as biomarkers is poor and most commonly related to autoantibodies anti-Hu and anti-CV2/CRMP-5 (collapsin response mediator protein 5) antibodies. |
