Acute disseminated histoplasmosis capsulati (Q96564): Difference between revisions

Acute disseminated histoplasmosis is a fulminant infection seen in people with impaired immune responses, particularly AIDS. It is characterised by pulmonary consolidation, enlargement of the liver and spleen, fever, anaemia, loss of appetite and generalised enlargement of lymph glands. Pulmonary manifestations may simulate miliary tuberculosis. Indurated granulomatous ulcers of the mouth, nose and larynx are often present and are distinctive. Progressive emaciation, induced by gastrointestinal involvement, contributes to a fatal outcome after a course of weeks or months. Cutaneous or mucocutaneous granulomas are often seen in association with disseminated disease.