Gorham-Stout disease (Q94226): Difference between revisions

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A doença de Gorham-Stout é definida como uma osteólise maciça, espontânea, caracterizada pela proliferação local de pequenos vasos sanguíneos ou linfáticos, resultando em destruição progressiva e reabsorção óssea. Os sinais clínicos iniciais incluem dor, edema e fraturas espontâneas. A osteólise pode parar de progredir a qualquer momento, mas muitas vezes o tecido ósseo desaparece completamente, deixando apenas uma faixa fibrosa residual, um desenvolvimento dramático que inspirou o termo “doença do osso desaparecido”.
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Gorham-Stout disease is defined as a spontaneous, massive osteolysis characterised by local proliferation of small vascular or lymphatic vessels resulting in progressive destruction and resorption of bone. Clinical signs at presentation include pain, swelling and spontaneous fractures. Osteolysis may stop progressing at any time, but often osseous tissue completely disappears, leaving only a residual fibrous band, a dramatic development inspiring the term 'vanishing bone disease.'

Revision as of 09:21, 16 August 2026

Gorham-Stout disease is defined as a spontaneous, massive osteolysis characterised by local proliferation of small vascular or lymphatic vessels resulting in progressive destruction and resorption of bone. Clinical signs at presentation include pain, swelling and spontaneous fractures. Osteolysis may stop progressing at any time, but often osseous tissue completely disappears, leaving only a residual fibrous band, a dramatic development inspiring the term 'vanishing bone disease.'
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    English
    Gorham-Stout disease
    Gorham-Stout disease is defined as a spontaneous, massive osteolysis characterised by local proliferation of small vascular or lymphatic vessels resulting in progressive destruction and resorption of bone. Clinical signs at presentation include pain, swelling and spontaneous fractures. Osteolysis may stop progressing at any time, but often osseous tissue completely disappears, leaving only a residual fibrous band, a dramatic development inspiring the term 'vanishing bone disease.'

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