Neutrophilic eccrine hidradenitis (Q90164): Difference between revisions
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Hidradenite écrina neutrofílica é uma erupção cutânea incomum caracterizada histologicamente por necrose do epitélio écrino e do ducto secretor écrino com um denso infiltrado neutrofílico circundante. A apresentação clínica típica é de máculas, nódulos ou placas purpúricas disseminadas ou solitárias que surgem em membros, pescoço, face e orelhas 8-10 dias após o início da quimioterapia para neoplasias, especialmente leucemia mieloide aguda. Frequentemente está associada a febre e pode ocasionalmente simular celulite bacteriana. Embora mais comumente associada à quimioterapia, tem sido relatada em associação com infecções em hospedeiros imunodeficientes e como um fenômeno paraneoplásico. | |||
| description / en | description / en | ||
Neutrophilic eccrine hidradenitis is an uncommon cutaneous eruption condition characterised histologically by necrosis of the eccrine epithelium and eccrine secretory coil with a dense surrounding neutrophilic infiltrate. The typical clinical presentation is of solitary or disseminated purpuric macules, nodules or plaques arising on the limbs, neck, face and ears 8–10 days after the start of chemotherapy for malignancy, especially acute myeloid leukaemia. It is often associated with fever and may on occasion simulate bacterial cellulitis. Although most commonly associated with chemotherapy, it has been reported in association with infections in immunodeficient hosts and as a paraneoplastic phenomenon. | |||
Revision as of 17:07, 15 August 2026
Neutrophilic eccrine hidradenitis is an uncommon cutaneous eruption condition characterised histologically by necrosis of the eccrine epithelium and eccrine secretory coil with a dense surrounding neutrophilic infiltrate. The typical clinical presentation is of solitary or disseminated purpuric macules, nodules or plaques arising on the limbs, neck, face and ears 8–10 days after the start of chemotherapy for malignancy, especially acute myeloid leukaemia. It is often associated with fever and may on occasion simulate bacterial cellulitis. Although most commonly associated with chemotherapy, it has been reported in association with infections in immunodeficient hosts and as a paraneoplastic phenomenon.
| Language | Label | Description | Also known as |
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| default for all languages | ID_789957175 |
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| English | Neutrophilic eccrine hidradenitis |
Neutrophilic eccrine hidradenitis is an uncommon cutaneous eruption condition characterised histologically by necrosis of the eccrine epithelium and eccrine secretory coil with a dense surrounding neutrophilic infiltrate. The typical clinical presentation is of solitary or disseminated purpuric macules, nodules or plaques arising on the limbs, neck, face and ears 8–10 days after the start of chemotherapy for malignancy, especially acute myeloid leukaemia. It is often associated with fever and may on occasion simulate bacterial cellulitis. Although most commonly associated with chemotherapy, it has been reported in association with infections in immunodeficient hosts and as a paraneoplastic phenomenon. |
