Sporadic inclusion body myopathy (Q88128): Difference between revisions
From determinar.ia.br - Determine suas informações
Created a new Item |
Changed label, description and/or aliases in pt-br, en |
||
| description / pt-br | description / pt-br | ||
Miosite esporádica por corpúsculo de inclusão é a miopatia adquirida mais frequente da meia-idade e da velhice e distingue-se de outras miopatias inflamatórias por seu padrão seletivo de envolvimento muscular e curso lentamente progressivo, e pela combinação de patologia muscular inflamatória e degenerativa e depósitos multiproteicos em tecido muscular. O fenótipo típico da doença inclui fraqueza e consumpção lentamente progressivas dos músculos quadríceps e do antebraço. Um grupo menor de pacientes apresenta inicialmente, por causa da fraqueza dos músculos flexores dos dedos longos ou fraqueza bulbar, com fraqueza dos membros inferiores ocorrendo em um estágio posterior. | |||
| description / en | description / en | ||
Sporadic inclusion body myositis is the most frequent acquired myopathy of middle and later life and is distinguished from other inflammatory myopathies by its selective pattern of muscle involvement and slowly progressive course, and by the combination of inflammatory and degenerative muscle pathology and multi-protein deposits in muscle tissue. Typical disease phenotype includes slowly progressive weakness and wasting of the quadriceps and forearm muscles. A smaller group of patients present initially because of weakness of the long finger flexor muscles or bulbar weakness, with lower limb weakness occurring at a later stage. | |||
Revision as of 14:14, 15 August 2026
Sporadic inclusion body myositis is the most frequent acquired myopathy of middle and later life and is distinguished from other inflammatory myopathies by its selective pattern of muscle involvement and slowly progressive course, and by the combination of inflammatory and degenerative muscle pathology and multi-protein deposits in muscle tissue. Typical disease phenotype includes slowly progressive weakness and wasting of the quadriceps and forearm muscles. A smaller group of patients present initially because of weakness of the long finger flexor muscles or bulbar weakness, with lower limb weakness occurring at a later stage.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | ID_983124715 |
||
| English | Sporadic inclusion body myopathy |
Sporadic inclusion body myositis is the most frequent acquired myopathy of middle and later life and is distinguished from other inflammatory myopathies by its selective pattern of muscle involvement and slowly progressive course, and by the combination of inflammatory and degenerative muscle pathology and multi-protein deposits in muscle tissue. Typical disease phenotype includes slowly progressive weakness and wasting of the quadriceps and forearm muscles. A smaller group of patients present initially because of weakness of the long finger flexor muscles or bulbar weakness, with lower limb weakness occurring at a later stage. |
