Autoimmune autonomic neuropathy (Q85114): Difference between revisions
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Neuropatias autonômicas autoimunes são doenças do sistema nervoso autônomo imunomediadas que podem ser limitadas, multifocais ou generalizadas (pan-disautonomia). O início pode ser subagudo ou insidioso e o teste autonômico geralmente revela anormalidades na função sudomotora, adrenérgica e cardiovagal. Pode ser autoimune ou paraneoplásico e acompanhado de autoanticorpos neurais. O distúrbio prototípico é uma ganglionopatia autoimune associada a autoanticorpos ganglionares nictônicos para receptores de acetilcolina [ver Neuropatia autonômica autoimune, definição positiva de anticorpos para receptores ganglionares de acetilcolina]. O rastreamento do câncer é apropriado para pessoas em risco. A disautonomia autoimune também pode ocorrer com a síndrome de Guillain-Barre [ver definição de síndrome de Guillain-Barre]. A exclusão de outras etiologias é apropriada se o diagnóstico for incerto. | |||
| description / en | description / en | ||
Autoimmune autonomic neuropathies are immune-mediated autonomic nervous system disorders which may be limited, multifocal or generalised (pan-dysautonomia). Onset may be subacute or insidious and autonomic testing usually reveals abnormalities in sudomotor, adrenergic and cardiovagal function. It may be autoimmune or paraneoplastic and accompanied by neural autoantibodies. The prototypic disorder is an autoimmune ganglionopathy associated with nictonic ganglionic-acetylcholine-receptor-autoantibodies [see Autoimmune autonomic neuropathy, ganglionic acetylcholine receptor antibody positive definition]. Screening for cancer is appropriate in those at risk. Autoimmune dysautonomia may also occur with Guillain-Barre syndrome [see Guillain-Barre syndrome definition]. Exclusion of other etiologies is appropriate if the diagnosis is uncertain. | |||
Revision as of 10:28, 15 August 2026
Autoimmune autonomic neuropathies are immune-mediated autonomic nervous system disorders which may be limited, multifocal or generalised (pan-dysautonomia). Onset may be subacute or insidious and autonomic testing usually reveals abnormalities in sudomotor, adrenergic and cardiovagal function. It may be autoimmune or paraneoplastic and accompanied by neural autoantibodies. The prototypic disorder is an autoimmune ganglionopathy associated with nictonic ganglionic-acetylcholine-receptor-autoantibodies [see Autoimmune autonomic neuropathy, ganglionic acetylcholine receptor antibody positive definition]. Screening for cancer is appropriate in those at risk. Autoimmune dysautonomia may also occur with Guillain-Barre syndrome [see Guillain-Barre syndrome definition]. Exclusion of other etiologies is appropriate if the diagnosis is uncertain.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | ID_343901465 |
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| English | Autoimmune autonomic neuropathy |
Autoimmune autonomic neuropathies are immune-mediated autonomic nervous system disorders which may be limited, multifocal or generalised (pan-dysautonomia). Onset may be subacute or insidious and autonomic testing usually reveals abnormalities in sudomotor, adrenergic and cardiovagal function. It may be autoimmune or paraneoplastic and accompanied by neural autoantibodies. The prototypic disorder is an autoimmune ganglionopathy associated with nictonic ganglionic-acetylcholine-receptor-autoantibodies [see Autoimmune autonomic neuropathy, ganglionic acetylcholine receptor antibody positive definition]. Screening for cancer is appropriate in those at risk. Autoimmune dysautonomia may also occur with Guillain-Barre syndrome [see Guillain-Barre syndrome definition]. Exclusion of other etiologies is appropriate if the diagnosis is uncertain. |
