Monoclonal gammopathy of undetermined significance-associated neuropathies (Q85113): Difference between revisions
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Gamopatia monoclonal de significado indeterminado (MGUS) pode estar associada a neuropatias sensitivas e motoras. MGUS está associada a uma cadeia de proteína M e ausência de lesões líticas do esqueleto. Existe um risco aumentado de mieloma. A neuropatia ocorre em até 30% dos pacientes, a incidência aumenta com a idade._x000D_ A paraproteinemia IgM também pode envolver: síndrome de Galop, GD1b, Gm1, gangliosídeo GM2/GalNAc-GD1a, glicoproteína associada à mielina, e condições associadas a sulfatídeo e tubulina. | |||
| description / en | description / en | ||
Monoclonal gammopathy of undetermined significance (MGUS) can be associated with sensory and motor neuropathies. MGUS is associated with an M-protein chain and absent lytic skeletal lesions. There is an increased risk to myeloma. Neuropathy occurs in up to 30 % of patients, the incidence increases with age. IgM paraproteinemia can also involve: Galop syndrome, GD1b, Gm1, GM2/GalNAc-GD1a ganglioside, myelin-associated glycoprotein, sulfatide and tubulin associated conditions. | |||
Revision as of 10:28, 15 August 2026
Monoclonal gammopathy of undetermined significance (MGUS) can be associated with sensory and motor neuropathies. MGUS is associated with an M-protein chain and absent lytic skeletal lesions. There is an increased risk to myeloma. Neuropathy occurs in up to 30 % of patients, the incidence increases with age. IgM paraproteinemia can also involve: Galop syndrome, GD1b, Gm1, GM2/GalNAc-GD1a ganglioside, myelin-associated glycoprotein, sulfatide and tubulin associated conditions.
| Language | Label | Description | Also known as |
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| default for all languages | ID_670961764 |
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| English | Monoclonal gammopathy of undetermined significance-associated neuropathies |
Monoclonal gammopathy of undetermined significance (MGUS) can be associated with sensory and motor neuropathies. MGUS is associated with an M-protein chain and absent lytic skeletal lesions. There is an increased risk to myeloma. Neuropathy occurs in up to 30 % of patients, the incidence increases with age. IgM paraproteinemia can also involve: Galop syndrome, GD1b, Gm1, GM2/GalNAc-GD1a ganglioside, myelin-associated glycoprotein, sulfatide and tubulin associated conditions. |
