Autoimmune motor neuropathy (Q85104): Difference between revisions
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A neuropatia motora pode apresentar uma distribuição simétrica e multifocal. O envolvimento sensorial está ausente ou mínimo. As extremidades superiores e os músculos bulbares são poupados. Alguns pacientes desenvolvem síndromes motoras inferiores assimétricas progressivas com fraqueza precoce predominante na musculatura proximal (síndromes P-LMN). Essas síndromes podem estar associadas à ligação de anticorpos ao gangliosídeo GA1. As síndromes de neurônio motor inferior proximais são caracterizados por um curso progressivo, diferente das neuropatias desmielinizantes como PIDC e neuropatia multifocal com bloqueio de condução. Os anticorpos associados podem ser GM1. | |||
| description / en | description / en | ||
Motor neuropathy can present in a symmetric and multifocal distribution. Sensory involvement is absent or minimal. Upper extremities and bulbar muscles are spared. Some patients develop progressive asymmetric lower motor syndromes with predominant early weakness in proximal musculature (P-LMN syndromes) These can be associated with antibody binding to GA1 ganglioside. LMND are characterised by a progressive course, different to the demyelinating neuropathies as CIDP and multifocal neuropathy with conduction block. Associated antibodies can be GM1. | |||
Revision as of 10:27, 15 August 2026
Motor neuropathy can present in a symmetric and multifocal distribution. Sensory involvement is absent or minimal. Upper extremities and bulbar muscles are spared. Some patients develop progressive asymmetric lower motor syndromes with predominant early weakness in proximal musculature (P-LMN syndromes) These can be associated with antibody binding to GA1 ganglioside. LMND are characterised by a progressive course, different to the demyelinating neuropathies as CIDP and multifocal neuropathy with conduction block. Associated antibodies can be GM1.
| Language | Label | Description | Also known as |
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| default for all languages | ID_253329991 |
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| English | Autoimmune motor neuropathy |
Motor neuropathy can present in a symmetric and multifocal distribution. Sensory involvement is absent or minimal. Upper extremities and bulbar muscles are spared. Some patients develop progressive asymmetric lower motor syndromes with predominant early weakness in proximal musculature (P-LMN syndromes) These can be associated with antibody binding to GA1 ganglioside. LMND are characterised by a progressive course, different to the demyelinating neuropathies as CIDP and multifocal neuropathy with conduction block. Associated antibodies can be GM1. |
