Serum sickness vasculitis (Q84950): Difference between revisions
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| description / pt-br | description / pt-br | ||
Doença vasculítica aguda caracterizada por febre, artralgia e vasculite urticariforme resultante de uma reação imune mediada por imunocomplexos (tipo III) a uma proteína estranha. Historicamente, isso se deveu em grande parte às antitoxinas e antiveninas derivadas do soro de cavalo. Embora a reação seja rara hoje em dia, os anticorpos policlonais e monoclonais preparados a partir de soro de cavalo, coelho ou camundongo (p.ex., globulina antitimócito, infliximabe e rituximabe) podem causar doença do soro da mesma forma que picadas de insetos (p.ex., abelhas e vespas) | |||
| description / en | description / en | ||
An acute vasculitic illness typified by fever, arthralgia and urticarial vasculitis resulting from an immune complex-mediated (type III) immune reaction to foreign protein. Historically this was largely due to horse-serum derived antitoxins and antivenins. Although the reaction is rare today, both polyclonal and monoclonal antibodies prepared from horse, rabbit, or mouse serum (e.g. antithymocyte globulin, infliximab and rituximab) may cause serum sickness, as may bites and stings (e.g. by bees and wasps) | |||
Revision as of 10:18, 15 August 2026
An acute vasculitic illness typified by fever, arthralgia and urticarial vasculitis resulting from an immune complex-mediated (type III) immune reaction to foreign protein. Historically this was largely due to horse-serum derived antitoxins and antivenins. Although the reaction is rare today, both polyclonal and monoclonal antibodies prepared from horse, rabbit, or mouse serum (e.g. antithymocyte globulin, infliximab and rituximab) may cause serum sickness, as may bites and stings (e.g. by bees and wasps)
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | ID_340796962 |
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| English | Serum sickness vasculitis |
An acute vasculitic illness typified by fever, arthralgia and urticarial vasculitis resulting from an immune complex-mediated (type III) immune reaction to foreign protein. Historically this was largely due to horse-serum derived antitoxins and antivenins. Although the reaction is rare today, both polyclonal and monoclonal antibodies prepared from horse, rabbit, or mouse serum (e.g. antithymocyte globulin, infliximab and rituximab) may cause serum sickness, as may bites and stings (e.g. by bees and wasps) |
