Autoimmune myelopathy (Q84149): Difference between revisions
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Mielopatias autoimunes são doenças imunomediadas da medula espinal. Os pacientes podem apresentar mielite transversa (que pode ser recidivante) ou mielopatia progressiva. Uma história pessoal ou familiar de outras doenças autoimunes (por exemplo, síndrome de Sjogren) é comum. Anormalidades na medula espinal na ressonância magnética e um fluido cefalorraquiano inflamatório são típicos. Autoanticorpos neurais específicos (por exemplo, detecção de Western blot de proteína 5 do mediador de resposta em colapso que pode ocorrer fora do cenário de câncer) e / ou autoanticorpos não órgão-específicos (por exemplo, anticorpos para o antígeno nuclear extraível) são frequentemente detectados. É importante excluir outras etiologias de mielite (por exemplo, infecções). | |||
| description / en | description / en | ||
Autoimmune myelopathies are immune mediated diseases of the spinal cord. Patients may present with transverse myelitis (which may be relapsing) or a progressive myelopathy. A personal or family history of other autoimmune disorders (e.g. Sjogren’s syndrome) is common. Abnormalities within the spinal cord on MRI and an inflammatory spinal fluid are typical. Neural specific autoantibodies (e.g. collapsing response mediator protein 5 western blot detection which may occur outside of the setting of cancer) and/or non-organ specific autoantibodies (e.g. antibodies to the extractable nuclear antigen) are often detected. It is important to exclude other myelitis etiologies (e.g. infections). | |||
Revision as of 09:30, 15 August 2026
Autoimmune myelopathies are immune mediated diseases of the spinal cord. Patients may present with transverse myelitis (which may be relapsing) or a progressive myelopathy. A personal or family history of other autoimmune disorders (e.g. Sjogren’s syndrome) is common. Abnormalities within the spinal cord on MRI and an inflammatory spinal fluid are typical. Neural specific autoantibodies (e.g. collapsing response mediator protein 5 western blot detection which may occur outside of the setting of cancer) and/or non-organ specific autoantibodies (e.g. antibodies to the extractable nuclear antigen) are often detected. It is important to exclude other myelitis etiologies (e.g. infections).
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | ID_1618667674 |
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| English | Autoimmune myelopathy |
Autoimmune myelopathies are immune mediated diseases of the spinal cord. Patients may present with transverse myelitis (which may be relapsing) or a progressive myelopathy. A personal or family history of other autoimmune disorders (e.g. Sjogren’s syndrome) is common. Abnormalities within the spinal cord on MRI and an inflammatory spinal fluid are typical. Neural specific autoantibodies (e.g. collapsing response mediator protein 5 western blot detection which may occur outside of the setting of cancer) and/or non-organ specific autoantibodies (e.g. antibodies to the extractable nuclear antigen) are often detected. It is important to exclude other myelitis etiologies (e.g. infections). |
