Paraneoplastic brainstem encephalitis (Q84128): Difference between revisions
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A encefalite paraneoplásica do tronco encefálico resulta de um ataque direcionado ao tronco encefálico como consequência de uma resposta imune tumoral potencialmente eficaz iniciada por antígenos onco-neurais derivados de um câncer sistêmico, resultando em sinais e sintomas subagudos (geralmente neuropatias cranianas múltiplas, também hipoventilação) relacionados ao tronco cerebral. Outros sintomas podem incluir laringoespasmo, distonia da abertura da mandíbula, opsoclonia-mioclonia e narcolepsia / cataplexia. O perfil de autoanticorpos no soro ou líquido cefalorraquidiano prediz o tipo de câncer [ver encefalite paraneoplásica do tronco cerebral: definição positiva de autoanticorpo neural]. A ressonância magnética pode ser normal ou revelar anormalidades do tronco cerebral e o líquido espinhal geralmente é inflamatório. Outras causas de encefalite do tronco cerebral (por exemplo, infecções) devem ser excluídas. | |||
| description / en | description / en | ||
Paraneoplastic brainstem encephalitis results from a targeted attack on the brainstem as a consequence of a potentially effective tumour immune response initiated by onco-neural antigens derived from a systemic cancer resulting in subacute symptoms and signs (usually multiple cranial neuropathies, also hypoventilation) referable to the brainstem. Other symptoms may include laryngospasm, jaw opening dystonia, opsoclonus-myoclonus and narcolepsy/cataplexy. The autoantibody profile in the serum or cerebrospinal fluid predicts the cancer type [see paraneoplastic brainstem encephalitis: neural autoantibody positive definition]. MRI may be normal or reveal brainstem abnormalities and spinal fluid is usually inflammatory. Other causes of brainstem encephalitis (e.g. infections) should be excluded. | |||
Revision as of 09:29, 15 August 2026
Paraneoplastic brainstem encephalitis results from a targeted attack on the brainstem as a consequence of a potentially effective tumour immune response initiated by onco-neural antigens derived from a systemic cancer resulting in subacute symptoms and signs (usually multiple cranial neuropathies, also hypoventilation) referable to the brainstem. Other symptoms may include laryngospasm, jaw opening dystonia, opsoclonus-myoclonus and narcolepsy/cataplexy. The autoantibody profile in the serum or cerebrospinal fluid predicts the cancer type [see paraneoplastic brainstem encephalitis: neural autoantibody positive definition]. MRI may be normal or reveal brainstem abnormalities and spinal fluid is usually inflammatory. Other causes of brainstem encephalitis (e.g. infections) should be excluded.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | ID_2061898171 |
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| English | Paraneoplastic brainstem encephalitis |
Paraneoplastic brainstem encephalitis results from a targeted attack on the brainstem as a consequence of a potentially effective tumour immune response initiated by onco-neural antigens derived from a systemic cancer resulting in subacute symptoms and signs (usually multiple cranial neuropathies, also hypoventilation) referable to the brainstem. Other symptoms may include laryngospasm, jaw opening dystonia, opsoclonus-myoclonus and narcolepsy/cataplexy. The autoantibody profile in the serum or cerebrospinal fluid predicts the cancer type [see paraneoplastic brainstem encephalitis: neural autoantibody positive definition]. MRI may be normal or reveal brainstem abnormalities and spinal fluid is usually inflammatory. Other causes of brainstem encephalitis (e.g. infections) should be excluded. |
