Paraneoplastic hyperexcitability syndrome with continuous muscle fibre activity (Q84061): Difference between revisions
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A síndrome de hiperexcitabilidade autoimune com atividade contínua da fibra muscular (CMFA), é uma síndrome neuromuscular rara caracterizada por fraqueza muscular, frequentemente miocimia, CMFA, às vezes uma cãibra e síndrome fasciculação e características autonômicas. Parestesia e hiperidrose também são comuns. Também os sintomas do SNC podem estar associados à síndrome de Morvan. Pode aparecer tanto como uma doença autoimune quanto paraneoplásica. Existe uma associação com o timoma._x000D_ _x000D_ A doença é suavizada por anticorpos mediados em particular com anticorpos do canal de potássio (VGKC) e o CASPR2 e menos subtipo LGII._x000D_ _x000D_ Ele responde à terapia sintomática e terapias imunológicas. | |||
| description / en | description / en | ||
The autoimmune hyperexcitability syndrome with CMFA, is a rare neuromuscular syndrome characterised by muscle weakness, often myokymia, CMFA, at times a cramp and fasciculation syndrome and autonomic features. Paraesthesia and hyperhydrosis are also common. Also CNS symptoms can be associated in Morvan`s syndrome. It can appear both as an autoimmune- and a paraneoplastic disease. An association with thymoma exists. The disease is soften antibody mediated in particular with potassium channel antibodies ( VGKC) and the CASPR2 and less LGII subtype. It responds to symptomatic therapy and immune therapies. | |||
Revision as of 09:25, 15 August 2026
The autoimmune hyperexcitability syndrome with CMFA, is a rare neuromuscular syndrome characterised by muscle weakness, often myokymia, CMFA, at times a cramp and fasciculation syndrome and autonomic features. Paraesthesia and hyperhydrosis are also common. Also CNS symptoms can be associated in Morvan`s syndrome. It can appear both as an autoimmune- and a paraneoplastic disease. An association with thymoma exists. The disease is soften antibody mediated in particular with potassium channel antibodies ( VGKC) and the CASPR2 and less LGII subtype. It responds to symptomatic therapy and immune therapies.
| Language | Label | Description | Also known as |
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| default for all languages | ID_1599858362 |
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| English | Paraneoplastic hyperexcitability syndrome with continuous muscle fibre activity |
The autoimmune hyperexcitability syndrome with CMFA, is a rare neuromuscular syndrome characterised by muscle weakness, often myokymia, CMFA, at times a cramp and fasciculation syndrome and autonomic features. Paraesthesia and hyperhydrosis are also common. Also CNS symptoms can be associated in Morvan`s syndrome. It can appear both as an autoimmune- and a paraneoplastic disease. An association with thymoma exists. The disease is soften antibody mediated in particular with potassium channel antibodies ( VGKC) and the CASPR2 and less LGII subtype. It responds to symptomatic therapy and immune therapies. |
