Autoimmune hyperexcitability syndrome with continuous muscle fibre activity or Morvan syndrome (Q84060): Difference between revisions
From determinar.ia.br - Determine suas informações
Created a new Item |
Changed label, description and/or aliases in pt-br, en |
||
| description / pt-br | description / pt-br | ||
A síndrome de hiperexcitabilidade autoimune com atividade contínua das fibras musculares (CMFA), é uma síndrome neuromuscular rara caracterizada por fraqueza muscular, frequentemente mioquimia, CMFA, às vezes uma cãibra e síndrome de fasciculação e características autonômicas. Parestesia e hiperidrose também são comuns. Também os sintomas do SNC podem estar associados à síndrome de Morvan. Pode aparecer tanto como uma doença autoimune quanto paraneoplásica. Existe uma associação com o timoma._x000D_ A doença é frequentemente mediada por anticorpos, em particular com anticorpos do canal de potássio (VGKC) e anti-CASPR2._x000D_ Ele responde à terapia sintomática e terapias imunológicas. | |||
| description / en | description / en | ||
The autoimmune hyperexcitability syndrome with continuous muscle fibre activity (CMFA), is a rare neuromuscular syndrome characterised by muscle weakness, often myokymia, CMFA, at times a cramp and fasciculation syndrome and autonomic features. Paraesthesia and hyperhydrosis are also common. Also CNS symptoms can be associated in Morvan`s syndrome. It can appear both as an autoimmune- and a paraneoplastic disease. An association with thymoma exists. The disease is often antibody mediated in particular with potassium channel antibodies (VGKC) and anti-CASPR2. It responds to symptomatic therapy and immune therapies. | |||
Revision as of 09:25, 15 August 2026
The autoimmune hyperexcitability syndrome with continuous muscle fibre activity (CMFA), is a rare neuromuscular syndrome characterised by muscle weakness, often myokymia, CMFA, at times a cramp and fasciculation syndrome and autonomic features. Paraesthesia and hyperhydrosis are also common. Also CNS symptoms can be associated in Morvan`s syndrome. It can appear both as an autoimmune- and a paraneoplastic disease. An association with thymoma exists. The disease is often antibody mediated in particular with potassium channel antibodies (VGKC) and anti-CASPR2. It responds to symptomatic therapy and immune therapies.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | ID_1155795500 |
||
| English | Autoimmune hyperexcitability syndrome with continuous muscle fibre activity or Morvan syndrome |
The autoimmune hyperexcitability syndrome with continuous muscle fibre activity (CMFA), is a rare neuromuscular syndrome characterised by muscle weakness, often myokymia, CMFA, at times a cramp and fasciculation syndrome and autonomic features. Paraesthesia and hyperhydrosis are also common. Also CNS symptoms can be associated in Morvan`s syndrome. It can appear both as an autoimmune- and a paraneoplastic disease. An association with thymoma exists. The disease is often antibody mediated in particular with potassium channel antibodies (VGKC) and anti-CASPR2. It responds to symptomatic therapy and immune therapies. |
