Benign gastrointestinal stromal tumour of large intestine (Q58433): Difference between revisions

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Revision as of 06:00, 14 August 2026

This is a benign mesenchymal tumour that arises from cells lining the large intestine. It is generally immunohitochemically positive for KIT (CD117), phenotypically paralleling Cajal-cell differentiation, and most examples contain KIT- or PDGFRA-activating mutations.
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    Benign gastrointestinal stromal tumour of large intestine
    This is a benign mesenchymal tumour that arises from cells lining the large intestine. It is generally immunohitochemically positive for KIT (CD117), phenotypically paralleling Cajal-cell differentiation, and most examples contain KIT- or PDGFRA-activating mutations.

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