Paraneoplastic acanthosis nigricans (Q55179): Difference between revisions
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Acredita-se que a acantose nigricans paraneoplásica seja devida à produção pelo tumor maligno associado de fatores que estimulam a proliferação de queratinócitos epidérmicos e fibroblastos dérmicos. É mais comumente relacionada a malignidade gastrointestinal subjacente. Em um terço dos casos precede o diagnóstico de câncer. Em contraste com a acantose nigricans benigna, frequentemente envolve as extremidades ("palma em tripa") e a cavidade oral. | |||
| description / en | description / en | ||
Paraneoplastic acanthosis nigricans is thought to be due to production by the associated malignant tumour of factors which stimulate epidermal keratinocyte and dermal fibroblast proliferation. It is most commonly linked to underlying gastro-intestinal malignancy. In a third of cases it precedes the diagnosis of cancer. In contrast with benign acanthosis nigricans it often involves the extremities (tripe palms) and oral cavity. | |||
Revision as of 02:49, 14 August 2026
Paraneoplastic acanthosis nigricans is thought to be due to production by the associated malignant tumour of factors which stimulate epidermal keratinocyte and dermal fibroblast proliferation. It is most commonly linked to underlying gastro-intestinal malignancy. In a third of cases it precedes the diagnosis of cancer. In contrast with benign acanthosis nigricans it often involves the extremities (tripe palms) and oral cavity.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | ID_915843260 |
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| English | Paraneoplastic acanthosis nigricans |
Paraneoplastic acanthosis nigricans is thought to be due to production by the associated malignant tumour of factors which stimulate epidermal keratinocyte and dermal fibroblast proliferation. It is most commonly linked to underlying gastro-intestinal malignancy. In a third of cases it precedes the diagnosis of cancer. In contrast with benign acanthosis nigricans it often involves the extremities (tripe palms) and oral cavity. |
