Human prion diseases (Q54308): Difference between revisions

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Doenças priônicas humanas ou encefalopatias espongiformes transmissíveis são doenças transmissíveis raras que afetam o sistema nervoso central. Os agentes infecciosos são compostos por uma isoforma anormal de uma proteína da membrana do hospedeiro chamada 'proteína priônica' (PrP). Suas características comuns são uma longa duração de incubação e lesões limitadas ao sistema nervoso central, sem reação inflamatória ou imunológica, mas com acúmulo de uma forma anormal de proteína príon (PrPsc).
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Human prion diseases or transmissible spongiform encephalopathies are rare transmissible diseases affecting the central nervous system. The infectious agents are composed of an abnormal isoform of a host membrane protein called 'prion protein' (PrP). Their common features are a long duration of incubation and lesions limited to the central nervous system without inflammatory or immunologic reaction but with accumulation of an abnormal form of prion protein (PrPsc).

Revision as of 01:55, 14 August 2026

Human prion diseases or transmissible spongiform encephalopathies are rare transmissible diseases affecting the central nervous system. The infectious agents are composed of an abnormal isoform of a host membrane protein called 'prion protein' (PrP). Their common features are a long duration of incubation and lesions limited to the central nervous system without inflammatory or immunologic reaction but with accumulation of an abnormal form of prion protein (PrPsc).
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    English
    Human prion diseases
    Human prion diseases or transmissible spongiform encephalopathies are rare transmissible diseases affecting the central nervous system. The infectious agents are composed of an abnormal isoform of a host membrane protein called 'prion protein' (PrP). Their common features are a long duration of incubation and lesions limited to the central nervous system without inflammatory or immunologic reaction but with accumulation of an abnormal form of prion protein (PrPsc).

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