Acute graft-versus-host disease (Q49235): Difference between revisions

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Doença do enxerto-versus-hospedeiro apresentando-se normalmente nos primeiros 100 dias após o transplante. Manifesta-se mais comumente com erupção maculopapular acompanhada de febre. O prognóstico se correlaciona com a extensão do acometimento cutâneo, que pode evoluir para necrólise epidérmica generalizada, e com a gravidade do acometimento gastrointestinal e hepático que pode se manifestar com diarreia e icterícia respectivamente. A mortalidade é alta na doença do enxerto-versus-hospedeiro aguda grave.
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Graft-versus-host disease presenting normally within the first 100 days of engraftment. It presents most commonly with a maculopapular rash accompanied by fever. The prognosis correlates with the extent of skin involvement, which may progress to widespread epidermal necrolysis, and the severity of gastrointestinal and liver involvement which may manifest as diarrhoea and jaundice respectively. There is a high mortality in severe acute graft-versus-host disease.

Revision as of 19:36, 13 August 2026

Graft-versus-host disease presenting normally within the first 100 days of engraftment. It presents most commonly with a maculopapular rash accompanied by fever. The prognosis correlates with the extent of skin involvement, which may progress to widespread epidermal necrolysis, and the severity of gastrointestinal and liver involvement which may manifest as diarrhoea and jaundice respectively. There is a high mortality in severe acute graft-versus-host disease.
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    English
    Acute graft-versus-host disease
    Graft-versus-host disease presenting normally within the first 100 days of engraftment. It presents most commonly with a maculopapular rash accompanied by fever. The prognosis correlates with the extent of skin involvement, which may progress to widespread epidermal necrolysis, and the severity of gastrointestinal and liver involvement which may manifest as diarrhoea and jaundice respectively. There is a high mortality in severe acute graft-versus-host disease.

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