Mucous membrane pemphigoid (Q43780): Difference between revisions

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O penfigoide de membrana mucosa (PMM) engloba um grupo heterogêneo de doenças autoimunes dominadas por membranas mucosas nas quais os autoanticorpos para antígenos da zona da membrana basal (ZBM) das membranas mucosas e da pele resultam em bolhas subepiteliais. A MMP pode ser limitada à conjuntiva (penfigóide ocular) ou à cavidade oral (penfigóide oral). Quando a pele está envolvida, geralmente é menos extensa e menos migratória do que no penfigoide bolhoso. A MMP segue um curso crônico e pode levar a cicatrizes graves com os riscos associados de perda de visão e estenose esofágica._x000D_ tudo
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Mucous membrane pemphigoid (MMP) encompasses a heterogeneous group of mucous membrane-dominated autoimmune diseases in which autoantibodies to antigens of the basement membrane zone (BMZ) of mucous membranes and the skin result in subepithelial blistering. MMP may be limited to the conjunctivae (ocular pemphigoid) or to the oral cavity (oral pemphigoid). When the skin is involved, it is generally less extensive and less migratory than in bullous pemphigoid. MMP follows a chronic course and may lead to severe scarring with the attendant risks of loss of vision and oesophageal strictures.

Revision as of 10:55, 13 August 2026

Mucous membrane pemphigoid (MMP) encompasses a heterogeneous group of mucous membrane-dominated autoimmune diseases in which autoantibodies to antigens of the basement membrane zone (BMZ) of mucous membranes and the skin result in subepithelial blistering. MMP may be limited to the conjunctivae (ocular pemphigoid) or to the oral cavity (oral pemphigoid). When the skin is involved, it is generally less extensive and less migratory than in bullous pemphigoid. MMP follows a chronic course and may lead to severe scarring with the attendant risks of loss of vision and oesophageal strictures.
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EB41.1
    English
    Mucous membrane pemphigoid
    Mucous membrane pemphigoid (MMP) encompasses a heterogeneous group of mucous membrane-dominated autoimmune diseases in which autoantibodies to antigens of the basement membrane zone (BMZ) of mucous membranes and the skin result in subepithelial blistering. MMP may be limited to the conjunctivae (ocular pemphigoid) or to the oral cavity (oral pemphigoid). When the skin is involved, it is generally less extensive and less migratory than in bullous pemphigoid. MMP follows a chronic course and may lead to severe scarring with the attendant risks of loss of vision and oesophageal strictures.

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