Secondary rhabdomyolysis (Q41410): Difference between revisions
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Rabdomiólise secundária ocorre quando o efeito primário de um fator etiológico resulta em um estado funcional ou bioquímico que conduz ao desenvolvimento de alterações isquêmicas, degenerativas, necróticas ou desestabilizadoras da membrana no músculo, produzindo as manifestações clínicas e bioquímicas de rabdomiólise. Mais frequentemente, a rabdomiólise é secundária a um desequilíbrio metabólico, muitas vezes de natureza genética, como resultado de movimento anormalmente excessivo, tensão isométrica excessiva por tentativa de movimento contra resistência, ou coma levando a aumento de pressão, isquemia, hipóxia e necrose intramusculares. A rabdomiólise secundária também pode ser causada por uma mutação em vários genes (RYR1, LPIN). | |||
| description / en | description / en | ||
Secondary rhabdomyolysis occurs when the primary effect of a aetiological factor results in a functional or biochemical state which is conducive to the development of ischemic, degenerative, necrotic or membrane destabilizing changes in muscle, producing the clinical and biochemical features of rhabdomyolysis. Most frequently, rhabdomyolysis is secondary to a metabolic derangement often genetic in nature, as result of abnormally excessive movement, excessive isometric tension by attempted movement against resistance, or coma leading to increased intramuscular pressure, ischemia, hypoxia and necrosis. Secondary rhabdomyolysis can also be caused by a mutation in various genes (RYR1, LPIN). | |||
Revision as of 07:34, 13 August 2026
Secondary rhabdomyolysis occurs when the primary effect of a aetiological factor results in a functional or biochemical state which is conducive to the development of ischemic, degenerative, necrotic or membrane destabilizing changes in muscle, producing the clinical and biochemical features of rhabdomyolysis. Most frequently, rhabdomyolysis is secondary to a metabolic derangement often genetic in nature, as result of abnormally excessive movement, excessive isometric tension by attempted movement against resistance, or coma leading to increased intramuscular pressure, ischemia, hypoxia and necrosis. Secondary rhabdomyolysis can also be caused by a mutation in various genes (RYR1, LPIN).
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | 8C84 |
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| English | Secondary rhabdomyolysis |
Secondary rhabdomyolysis occurs when the primary effect of a aetiological factor results in a functional or biochemical state which is conducive to the development of ischemic, degenerative, necrotic or membrane destabilizing changes in muscle, producing the clinical and biochemical features of rhabdomyolysis. Most frequently, rhabdomyolysis is secondary to a metabolic derangement often genetic in nature, as result of abnormally excessive movement, excessive isometric tension by attempted movement against resistance, or coma leading to increased intramuscular pressure, ischemia, hypoxia and necrosis. Secondary rhabdomyolysis can also be caused by a mutation in various genes (RYR1, LPIN). |
