Myasthenia gravis (Q41373): Difference between revisions
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Miastenia gravis é o transtorno de transmissão neuromuscular mediado por autoanticorpo adquirido mais comum. A prevalência é de 1–2 por 10.000 pessoas. Fraqueza flutuante aumentando com a atividade repetida e melhorando após um período de descanso é a marca característica. Miastenia Gravis com anticorpos dirigidos contra proteínas pós-sinápticas, geralmente o receptor nicotínico de acetilcolina, são as mais prevalentes. Outros tipos são Miastenia Gravis associada a anticorpos quinase específicos do músculo e Miastenia Gravis com autoanticorpos desconhecidos (soronegativos)._x000D_ Existem três grupos: _x000D_ 1. Miastenia Gravis puramente ocular_x000D_ 2. Miastenia Gravis generalizada de início precoce (<40-50 anos)_x000D_ 3. MG generalizada de início tardio._x000D_ Em cerca de 15%, a doença pode ser classificada como paraneoplásica, geralmente associada a um timoma. | |||
| description / en | description / en | ||
Myasthenia gravis is the most common acquired auto-antibody mediated neuromuscular transmission disorder. Prevalence is 1–2 per 10,000 persons. Fluctuating weakness increasing with repeated activity and improving after a period of rest is the hallmark. Myasthenia Gravis with antibodies directed against postsynaptic proteins, usually the nicotinic acetylcholine receptor are the most prevalent. Other types are Myasthenia Gravis associated with muscle-specific kinase antibodies and MG with unknown autoantibodies (seronegative) Myasthenia Gravis. There are three groups: 1. Purely ocular Myasthenia Gravis 2. Early-onset (<40-50 years) generalised Myasthenia Gravis 3. Late-onset generalised MG. In about 15%, the disease can be classified as paraneoplastic, usually associated with a thymoma. | |||
Revision as of 07:31, 13 August 2026
Myasthenia gravis is the most common acquired auto-antibody mediated neuromuscular transmission disorder. Prevalence is 1–2 per 10,000 persons. Fluctuating weakness increasing with repeated activity and improving after a period of rest is the hallmark. Myasthenia Gravis with antibodies directed against postsynaptic proteins, usually the nicotinic acetylcholine receptor are the most prevalent. Other types are Myasthenia Gravis associated with muscle-specific kinase antibodies and MG with unknown autoantibodies (seronegative) Myasthenia Gravis. There are three groups: 1. Purely ocular Myasthenia Gravis 2. Early-onset (<40-50 years) generalised Myasthenia Gravis 3. Late-onset generalised MG. In about 15%, the disease can be classified as paraneoplastic, usually associated with a thymoma.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | 8C60 |
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| English | Myasthenia gravis |
Myasthenia gravis is the most common acquired auto-antibody mediated neuromuscular transmission disorder. Prevalence is 1–2 per 10,000 persons. Fluctuating weakness increasing with repeated activity and improving after a period of rest is the hallmark. Myasthenia Gravis with antibodies directed against postsynaptic proteins, usually the nicotinic acetylcholine receptor are the most prevalent. Other types are Myasthenia Gravis associated with muscle-specific kinase antibodies and MG with unknown autoantibodies (seronegative) Myasthenia Gravis. There are three groups: 1. Purely ocular Myasthenia Gravis 2. Early-onset (<40-50 years) generalised Myasthenia Gravis 3. Late-onset generalised MG. In about 15%, the disease can be classified as paraneoplastic, usually associated with a thymoma. |
