Vitamin A deficiency with corneal ulceration or keratomalacia (Q39908): Difference between revisions
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Ulceração / ceratomalácia indica destruição permanente de parte ou de todo o estroma corneano, resultando em alteração estrutural permanente. As úlceras são classicamente arredondadas a ovais, "perfuradas", como se uma furadeira ou uma broca de cortiça tivessem sido aplicadas no olho. A córnea circundante é geralmente xerótica, mas, por outro lado, clara, e normalmente não tem a aparência cinzenta e infiltrada de úlceras de origem bacteriana. Pode haver mais de uma úlcera. As pequenas úlceras estão quase invariavelmente confinadas à periferia da córnea, especialmente em sua face inferior e nasal. A ulceração pode ser superficial, mas geralmente é profunda. As perfurações ficam ligadas com a íris, preservando assim a câmara anterior. Na doença mais avançada, o estroma necrótico descama, deixando uma grande úlcera ou descemetocele. Tal como acontece com úlceras menores, geralmente é periférica e cura como um leucoma denso, branco e aderente. Com a terapia, as úlceras superficiais costumam cicatrizar surpreendentemente com poucas cicatrizes; úlceras mais profundas, especialmente perfurações, formam densos leucomas periféricos aderentes. | |||
| description / en | description / en | ||
Ulceration/keratomalacia indicates permanent destruction of part or all of the corneal stroma, resulting in permanent structural alteration. Ulcers are classically round to oval "punched-out" defects, as if a trephine or cork-borer had been applied to the eye. The surrounding cornea is generally xerotic but otherwise clear, and typically lacks the grey, infiltrated appearance of ulcers of bacterial origin. There may be more than one ulcer. Small ulcers are almost invariably confined to the periphery of the cornea, especially its inferior and nasal aspects. The ulceration may be shallow, but is commonly deep. Perforations become plugged with iris, thereby preserving the anterior chamber. In more advanced disease the necrotic stroma sloughs, leaving a large ulcer or descemetocele. As with smaller ulcers, this is usually peripheral and heals as a dense, white, adherent leukoma. With therapy, superficial ulcers often heal with surprisingly little scarring; deeper ulcers, especially perforations, form dense peripheral adherent leukomas. | |||
Revision as of 05:30, 13 August 2026
Ulceration/keratomalacia indicates permanent destruction of part or all of the corneal stroma, resulting in permanent structural alteration. Ulcers are classically round to oval "punched-out" defects, as if a trephine or cork-borer had been applied to the eye. The surrounding cornea is generally xerotic but otherwise clear, and typically lacks the grey, infiltrated appearance of ulcers of bacterial origin. There may be more than one ulcer. Small ulcers are almost invariably confined to the periphery of the cornea, especially its inferior and nasal aspects. The ulceration may be shallow, but is commonly deep. Perforations become plugged with iris, thereby preserving the anterior chamber. In more advanced disease the necrotic stroma sloughs, leaving a large ulcer or descemetocele. As with smaller ulcers, this is usually peripheral and heals as a dense, white, adherent leukoma. With therapy, superficial ulcers often heal with surprisingly little scarring; deeper ulcers, especially perforations, form dense peripheral adherent leukomas.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | 5B55.4 |
||
| English | Vitamin A deficiency with corneal ulceration or keratomalacia |
Ulceration/keratomalacia indicates permanent destruction of part or all of the corneal stroma, resulting in permanent structural alteration. Ulcers are classically round to oval "punched-out" defects, as if a trephine or cork-borer had been applied to the eye. The surrounding cornea is generally xerotic but otherwise clear, and typically lacks the grey, infiltrated appearance of ulcers of bacterial origin. There may be more than one ulcer. Small ulcers are almost invariably confined to the periphery of the cornea, especially its inferior and nasal aspects. The ulceration may be shallow, but is commonly deep. Perforations become plugged with iris, thereby preserving the anterior chamber. In more advanced disease the necrotic stroma sloughs, leaving a large ulcer or descemetocele. As with smaller ulcers, this is usually peripheral and heals as a dense, white, adherent leukoma. With therapy, superficial ulcers often heal with surprisingly little scarring; deeper ulcers, especially perforations, form dense peripheral adherent leukomas. |
