Heavy chain deposition disease (Q39451): Difference between revisions
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Doença do rim, causada por proliferação e deposição de pedaços de segmentos de cadeia pesada de imunoglobulina alfa, gama, delta ou mu truncados ou anormais de leucócitos. Esta doença é caracterizada por depósitos de tecido fibrilar ou granular e disfunção renal, que podem levar à falência do órgão. A confirmação é feita pela identificação de deposição de cadeia pesada em tecido biopsiado, usando imunofluorescência ao microscópio. | |||
| description / en | description / en | ||
A disease of the kidney, caused by proliferation and deposition of pieces of truncated or abnormal alpha, gamma, delta, or mu immunoglobulin heavy chain segments of white blood cells. This disease is characterised by fibrillar or granular tissue deposits and renal dysfunction, which may lead to organ failure. Confirmation is by identifying heavy chain deposition tissue biopsy using immunofluorescence under a microscope. | |||
Revision as of 04:52, 13 August 2026
A disease of the kidney, caused by proliferation and deposition of pieces of truncated or abnormal alpha, gamma, delta, or mu immunoglobulin heavy chain segments of white blood cells. This disease is characterised by fibrillar or granular tissue deposits and renal dysfunction, which may lead to organ failure. Confirmation is by identifying heavy chain deposition tissue biopsy using immunofluorescence under a microscope.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | 2A83.50 |
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| English | Heavy chain deposition disease |
A disease of the kidney, caused by proliferation and deposition of pieces of truncated or abnormal alpha, gamma, delta, or mu immunoglobulin heavy chain segments of white blood cells. This disease is characterised by fibrillar or granular tissue deposits and renal dysfunction, which may lead to organ failure. Confirmation is by identifying heavy chain deposition tissue biopsy using immunofluorescence under a microscope. |
