Anaplastic large cell lymphoma, ALK-positive (Q39110): Difference between revisions
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Linfoma periférico de células T composto por linfócitos T geralmente grandes, pleomórficos, CD30 positivos com citoplasma abundante, caracterizado pela presença de uma translocação envolvendo o gene ALK e a expressão da proteína de fusão ALK. A maioria dos pacientes apresenta linfadenopatia periférica e/ou abdominal e frequentemente tem doença avançada e envolvimento extranodal. | |||
| description / en | description / en | ||
A T-cell peripheral lymphoma composed of usually large, pleomorphic, CD30 positive T-lymphocytes with abundant cytoplasm characterised by the presence of a translocation involving the ALK gene and expression of ALK fusion protein. Most patients present with peripheral and/or abdominal lymphadenopathy, and often have advanced disease and extranodal involvement. | |||
Revision as of 04:25, 13 August 2026
A T-cell peripheral lymphoma composed of usually large, pleomorphic, CD30 positive T-lymphocytes with abundant cytoplasm characterised by the presence of a translocation involving the ALK gene and expression of ALK fusion protein. Most patients present with peripheral and/or abdominal lymphadenopathy, and often have advanced disease and extranodal involvement.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | 2A90.A |
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| English | Anaplastic large cell lymphoma, ALK-positive |
A T-cell peripheral lymphoma composed of usually large, pleomorphic, CD30 positive T-lymphocytes with abundant cytoplasm characterised by the presence of a translocation involving the ALK gene and expression of ALK fusion protein. Most patients present with peripheral and/or abdominal lymphadenopathy, and often have advanced disease and extranodal involvement. |
