Synovial sarcoma, primary site (Q38802): Difference between revisions
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Neoplasia maligna caracterizada pela translocação cromossômica t (X; 18) (p11; q11). Pode ocorrer em qualquer idade, mas afeta principalmente adultos jovens, mais comumente do sexo masculino. Embora qualquer local possa ser afetado, a grande maioria dos casos surge nos tecidos moles profundos das extremidades, especialmente ao redor do joelho. Microscopicamente, o sarcoma sinovial é classificado como monofásico (com células fusiformes ou componente de célula epitelial) ou bifásico (com componentes de células epiteliais e de células fusiformes). Os sarcomas sinoviais podem recidivar ou desenvolver metástases para os pulmões, ossos e nódulos linfáticos. | |||
| description / en | description / en | ||
A malignant neoplasm characterised by the chromosomal translocation t(X;18)(p11;q11). It can occur at any age, but mainly affects young adults, more commonly males. Although any site can be affected, the vast majority of the cases arise in the deep soft tissues of extremities, especially around the knee. Microscopically, synovial sarcoma is classified as monophasic (with a spindle or epithelial cell component) or biphasic (with both spindle and epithelial cell components). Synovial sarcomas can recur or metastasize to the lungs, bones, and lymph nodes. | |||
Revision as of 04:01, 13 August 2026
A malignant neoplasm characterised by the chromosomal translocation t(X;18)(p11;q11). It can occur at any age, but mainly affects young adults, more commonly males. Although any site can be affected, the vast majority of the cases arise in the deep soft tissues of extremities, especially around the knee. Microscopically, synovial sarcoma is classified as monophasic (with a spindle or epithelial cell component) or biphasic (with both spindle and epithelial cell components). Synovial sarcomas can recur or metastasize to the lungs, bones, and lymph nodes.
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | 2B5A |
||
| English | Synovial sarcoma, primary site |
A malignant neoplasm characterised by the chromosomal translocation t(X;18)(p11;q11). It can occur at any age, but mainly affects young adults, more commonly males. Although any site can be affected, the vast majority of the cases arise in the deep soft tissues of extremities, especially around the knee. Microscopically, synovial sarcoma is classified as monophasic (with a spindle or epithelial cell component) or biphasic (with both spindle and epithelial cell components). Synovial sarcomas can recur or metastasize to the lungs, bones, and lymph nodes. |
