Short stature due to primary acid-labile subunit deficiency (Q106514): Difference between revisions

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Revision as of 13:30, 17 August 2026

Short stature due to primary acid-labile subunit (ALS) deficiency is defined by moderate postnatal growth deficit, markedly low circulating levels of insulin-like growth factor 1 (IGF-1) and insulin-like growth factor binding protein 3 (IGFBP-3), and hyperinsulinemia, in the absence of growth hormone (GH) deficiency or GH insensitivity.
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    Short stature due to primary acid-labile subunit deficiency
    Short stature due to primary acid-labile subunit (ALS) deficiency is defined by moderate postnatal growth deficit, markedly low circulating levels of insulin-like growth factor 1 (IGF-1) and insulin-like growth factor binding protein 3 (IGFBP-3), and hyperinsulinemia, in the absence of growth hormone (GH) deficiency or GH insensitivity.

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